EVIDENCE BY TOPIC

Prescribing cascades

Sequences in which an adverse drug effect is interpreted as a new condition and treated with an additional medication.

The entries below are connected by subject, not arranged as a protocol or a complete literature review.

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Input System

1 claim

A prescribing cascade can occur when an adverse drug effect is misread as a new condition and treated with another medication; one documented calcium-channel-blocker/diuretic cascade in older adults has been associated with higher rates of serious adverse events.

Strong human evidence

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Last reviewed: September 15, 2026

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